MovDisordV3, Main, Exploration, bibRecord, 003664

Cardiac [123I]metaiodobenzylguanidine scintigraphy for vascular parkinsonism

Identifieur interne : 003664 ( Main/Exploration ); précédent : 003663; suivant : 003665

Cardiac [123I]metaiodobenzylguanidine scintigraphy for vascular parkinsonism

Auteurs : Joong-Seok Kim [Corée du Sud] ; Phil-Hyu Lee [Corée du Sud] ; Kwang-Soo Lee [Corée du Sud] ; Jeong-Wook Park [Corée du Sud] ; Yeong-In Kim [Corée du Sud] ; Yong-An Chung [Corée du Sud] ; Sung-Hoon Kim [Corée du Sud] ; Seung-Hyun Kim [Corée du Sud] ; Juhan Kim [Corée du Sud] ; Yun-Young Choi [Corée du Sud] ; Hee-Tae Kim [Corée du Sud]

Source :

Movement disorders [ 0885-3185 ] ; 2006.

RBID : Pascal:07-0021733

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Parkinsonisme, Parkinson maladie, Scintigraphie.

English descriptors

KwdEn :
- Nervous system diseases, Parkinson disease, Parkinsonism, Scintigraphy.

Abstract

The purpose of our study was to prospectively evaluate cardiac [¹²³I]metaiodobenzylguanidine (MIBG) uptake in patients with cerebrovascular disease (CVD) who develop clinical symptoms of vascular Parkinsonism (VP). A total of 19 consecutive patients who developed Parkinsonism during the course of their CVD were enrolled in the study; 15 age-matched subjects, and 29 patients with Parkinson's disease (PD) were also evaluated with cardiac MIBG uptake. MIBG uptake was assessed using the ratio of the heart to the upper mediastinum (H/M) according to planar scintigraphic data. The mean H/M ratio was significantly higher in patients with VP than in those with PD (2.28 ± 0.41 vs. 1.27 ± 0.13; P < 0.001). MIBG uptake did not differ between VP and controls (2.46 ± 0.33; P > 0.05). Our findings suggest that myocardial postganglionic sympathetic dysfunction found in PD is absent in most patients with VP. MIBG single photon emission computed tomography imaging may be useful to help distinguish between PD and VP patients in clinical practice.

Affiliations:

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Le document en format XML

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I]metaiodobenzylguanidine scintigraphy for vascular parkinsonism</title>
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<author><name sortKey="Chung, Yong An" sort="Chung, Yong An" uniqKey="Chung Y" first="Yong-An" last="Chung">Yong-An Chung</name>
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<author><name sortKey="Kim, Sung Hoon" sort="Kim, Sung Hoon" uniqKey="Kim S" first="Sung-Hoon" last="Kim">Sung-Hoon Kim</name>
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<author><name sortKey="Kim, Seung Hyun" sort="Kim, Seung Hyun" uniqKey="Kim S" first="Seung-Hyun" last="Kim">Seung-Hyun Kim</name>
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<author><name sortKey="Kim, Juhan" sort="Kim, Juhan" uniqKey="Kim J" first="Juhan" last="Kim">Juhan Kim</name>
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<author><name sortKey="Choi, Yun Young" sort="Choi, Yun Young" uniqKey="Choi Y" first="Yun-Young" last="Choi">Yun-Young Choi</name>
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<s3>KOR</s3>
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<country>Corée du Sud</country>
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<author><name sortKey="Kim, Hee Tae" sort="Kim, Hee Tae" uniqKey="Kim H" first="Hee-Tae" last="Kim">Hee-Tae Kim</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Neurology, Hanyang University Medical College</s1>
<s2>Seoul</s2>
<s3>KOR</s3>
<sZ>8 aut.</sZ>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Cardiac [<sup>123</sup>
I]metaiodobenzylguanidine scintigraphy for vascular parkinsonism</title>
<author><name sortKey="Kim, Joong Seok" sort="Kim, Joong Seok" uniqKey="Kim J" first="Joong-Seok" last="Kim">Joong-Seok Kim</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, The Catholic University of Korea</s1>
<s2>Seoul</s2>
<s3>KOR</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
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</inist:fA14>
<country>Corée du Sud</country>
<placeName><settlement type="city">Séoul</settlement>
</placeName>
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</author>
<author><name sortKey="Lee, Phil Hyu" sort="Lee, Phil Hyu" uniqKey="Lee P" first="Phil-Hyu" last="Lee">Phil-Hyu Lee</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Neurology, Ajou University Medical College</s1>
<s2>Suwon</s2>
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<author><name sortKey="Lee, Kwang Soo" sort="Lee, Kwang Soo" uniqKey="Lee K" first="Kwang-Soo" last="Lee">Kwang-Soo Lee</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, The Catholic University of Korea</s1>
<s2>Seoul</s2>
<s3>KOR</s3>
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<sZ>3 aut.</sZ>
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<author><name sortKey="Park, Jeong Wook" sort="Park, Jeong Wook" uniqKey="Park J" first="Jeong-Wook" last="Park">Jeong-Wook Park</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, The Catholic University of Korea</s1>
<s2>Seoul</s2>
<s3>KOR</s3>
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<country>Corée du Sud</country>
<placeName><settlement type="city">Séoul</settlement>
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</author>
<author><name sortKey="Kim, Yeong In" sort="Kim, Yeong In" uniqKey="Kim Y" first="Yeong-In" last="Kim">Yeong-In Kim</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Neurology, The Catholic University of Korea</s1>
<s2>Seoul</s2>
<s3>KOR</s3>
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<country>Corée du Sud</country>
<placeName><settlement type="city">Séoul</settlement>
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</author>
<author><name sortKey="Chung, Yong An" sort="Chung, Yong An" uniqKey="Chung Y" first="Yong-An" last="Chung">Yong-An Chung</name>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Nuclear Medicine, The Catholic University of Korea</s1>
<s2>Seoul</s2>
<s3>KOR</s3>
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</inist:fA14>
<country>Corée du Sud</country>
<placeName><settlement type="city">Séoul</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kim, Sung Hoon" sort="Kim, Sung Hoon" uniqKey="Kim S" first="Sung-Hoon" last="Kim">Sung-Hoon Kim</name>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Nuclear Medicine, The Catholic University of Korea</s1>
<s2>Seoul</s2>
<s3>KOR</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<placeName><settlement type="city">Séoul</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kim, Seung Hyun" sort="Kim, Seung Hyun" uniqKey="Kim S" first="Seung-Hyun" last="Kim">Seung-Hyun Kim</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Neurology, Hanyang University Medical College</s1>
<s2>Seoul</s2>
<s3>KOR</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<placeName><settlement type="city">Séoul</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kim, Juhan" sort="Kim, Juhan" uniqKey="Kim J" first="Juhan" last="Kim">Juhan Kim</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Neurology, Hanyang University Medical College</s1>
<s2>Seoul</s2>
<s3>KOR</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<placeName><settlement type="city">Séoul</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Choi, Yun Young" sort="Choi, Yun Young" uniqKey="Choi Y" first="Yun-Young" last="Choi">Yun-Young Choi</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Department of Nuclear Medicine, Hanyang University Medical College</s1>
<s2>Seoul</s2>
<s3>KOR</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<placeName><settlement type="city">Séoul</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kim, Hee Tae" sort="Kim, Hee Tae" uniqKey="Kim H" first="Hee-Tae" last="Kim">Hee-Tae Kim</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Neurology, Hanyang University Medical College</s1>
<s2>Seoul</s2>
<s3>KOR</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<placeName><settlement type="city">Séoul</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2006">2006</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Nervous system diseases</term>
<term>Parkinson disease</term>
<term>Parkinsonism</term>
<term>Scintigraphy</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Parkinsonisme</term>
<term>Parkinson maladie</term>
<term>Scintigraphie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The purpose of our study was to prospectively evaluate cardiac [<sup>123</sup>
I]metaiodobenzylguanidine (MIBG) uptake in patients with cerebrovascular disease (CVD) who develop clinical symptoms of vascular Parkinsonism (VP). A total of 19 consecutive patients who developed Parkinsonism during the course of their CVD were enrolled in the study; 15 age-matched subjects, and 29 patients with Parkinson's disease (PD) were also evaluated with cardiac MIBG uptake. MIBG uptake was assessed using the ratio of the heart to the upper mediastinum (H/M) according to planar scintigraphic data. The mean H/M ratio was significantly higher in patients with VP than in those with PD (2.28 ± 0.41 vs. 1.27 ± 0.13; P < 0.001). MIBG uptake did not differ between VP and controls (2.46 ± 0.33; P > 0.05). Our findings suggest that myocardial postganglionic sympathetic dysfunction found in PD is absent in most patients with VP. MIBG single photon emission computed tomography imaging may be useful to help distinguish between PD and VP patients in clinical practice.</div>
</front>
</TEI>
<affiliations><list><country><li>Corée du Sud</li>
</country>
<settlement><li>Séoul</li>
</settlement>
</list>
<tree><country name="Corée du Sud"><noRegion><name sortKey="Kim, Joong Seok" sort="Kim, Joong Seok" uniqKey="Kim J" first="Joong-Seok" last="Kim">Joong-Seok Kim</name>
</noRegion>
<name sortKey="Choi, Yun Young" sort="Choi, Yun Young" uniqKey="Choi Y" first="Yun-Young" last="Choi">Yun-Young Choi</name>
<name sortKey="Chung, Yong An" sort="Chung, Yong An" uniqKey="Chung Y" first="Yong-An" last="Chung">Yong-An Chung</name>
<name sortKey="Kim, Hee Tae" sort="Kim, Hee Tae" uniqKey="Kim H" first="Hee-Tae" last="Kim">Hee-Tae Kim</name>
<name sortKey="Kim, Juhan" sort="Kim, Juhan" uniqKey="Kim J" first="Juhan" last="Kim">Juhan Kim</name>
<name sortKey="Kim, Seung Hyun" sort="Kim, Seung Hyun" uniqKey="Kim S" first="Seung-Hyun" last="Kim">Seung-Hyun Kim</name>
<name sortKey="Kim, Sung Hoon" sort="Kim, Sung Hoon" uniqKey="Kim S" first="Sung-Hoon" last="Kim">Sung-Hoon Kim</name>
<name sortKey="Kim, Yeong In" sort="Kim, Yeong In" uniqKey="Kim Y" first="Yeong-In" last="Kim">Yeong-In Kim</name>
<name sortKey="Lee, Kwang Soo" sort="Lee, Kwang Soo" uniqKey="Lee K" first="Kwang-Soo" last="Lee">Kwang-Soo Lee</name>
<name sortKey="Lee, Phil Hyu" sort="Lee, Phil Hyu" uniqKey="Lee P" first="Phil-Hyu" last="Lee">Phil-Hyu Lee</name>
<name sortKey="Park, Jeong Wook" sort="Park, Jeong Wook" uniqKey="Park J" first="Jeong-Wook" last="Park">Jeong-Wook Park</name>
</country>
</tree>
</affiliations>
</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Cardiac [123I]metaiodobenzylguanidine scintigraphy for vascular parkinsonism

Cardiac [123I]metaiodobenzylguanidine scintigraphy for vascular parkinsonism

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri